Coronavirus: why not only age and previous illnesses would determine the most serious cases

Factors influencing the prognosis and severity of cases of COVID-19 are one of the current questions for scientists.

On this, a study published in “The New England Journal of Medicine” and then taken in Spanish newspaper ABC gave some guidelines.

The work, which had the participation of Biomedical Research Center of Spain and professionals from different European countries with a high incidence of cases, suggests that the development of severe clinical forms could be associated with variants of the human genome located on chromosome 3, which would favor the entry of the virus.

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COVID. 19 could develop more severe cases in people with a certain genetoca (Shutterstock).

COVID. 19 could develop more severe cases in people with a certain genetoca (Shutterstock).

The second option would be located on chromosome 9, specifically in the gene that determines the blood group. Whereupon, eBlood group A would initially be associated with a 50% increased risk of needing respiratory support in the event of this infection.. Conversely, blood group O would provide a protective effect.

This guideline is in accordance with the coordinated study by Andre Franke, molecular geneticist at the University of Kiel (Germany), on the extra risk of people with type A blood.

The research was conducted at the European peak of the pandemic and a higher frequency of 26 genetic variants was identified in patients affected by respiratory failure.

The results could more precisely determine vulnerable people, provide them with special protection and design personalized treatments. Which would imply important advances.

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